Zgwatinib


CAS No. : 1268264-10-3

(Synonyms: SOMG-833)

1268264-10-3
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Cat. No. : HY-124267
M.Wt: 445.44
Formula: C22H22F3N5O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1268264-10-3 :

Zgwatinib (SOMG-833) is a potent, selective, and ATP-competitive c-MET inhibitor, with an IC50 of 0.93 nM against c-MET, over 10,000-fold more potent compared with 19 tyrosine kinases (including c-MET family members and highly homologous kinases). Zgwatinib potently inhibits c-MET-driven cell proliferation. Zgwatinib as a potential candidate agent for c-MET-driven human cancers research[1]. IC50 & Target:IC50: 0.93 nM (c-MET)[1]

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