PX20606
CAS No. : 1268245-19-7
(Synonyms: PX-102)
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| Cat. No. : | HY-100443 |
| M.Wt: | 554.85 |
| Formula: | C29H22Cl3NO4 |
| Purity: | >98 % |
| Solubility: |
PX20606 is an orally active agonist for farnesoid X receptor (FXR), with EC50 220 nM (mFXR) and 50 nM (hFXR), measured by Gal4-FXR assay. PX20606 induces the expression of tumor suppressor gene NDRG2, inhibits the tumor growth and metastasis in mouse HCC model. PX20606 exhibits hepatoprotective efficacy[1].
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