Angiotensin II (3-8), human
CAS No. : 12676-15-2
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| Cat. No. : | HY-P1515 |
| M.Wt: | 774.91 |
| Formula: | C40H54N8O8 |
| Purity: | >98 % |
| Solubility: | 10 mM in H2O |
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor. IC50 & Target: Angiotensin AT1 receptor[1] In Vivo: Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances[1].
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