(E)-Hyzetimibe


CAS No. : 1266548-75-7

(Synonyms: (E)-HS-25)

1266548-75-7
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Cat. No. : HY-107176
M.Wt: 421.44
Formula: C25H21F2NO3
Purity: >98 %
Solubility:
Introduction of 1266548-75-7 :

(E)-Hyzetimibe ((E)-HS-25) (Compound I-1Z) is the trans isomer of Hyzetimibe (HY-107176A), a cholesterol-lowering agent. (E)-Hyzetimibe has cholesterol acyltransferase (ACTA) inhibitory activity, but its cholesterol-lowering effect is relatively weak. (E)-Hyzetimibe can inhibit the entry of hepatitis C virus (HCV) into host cells, and it has a synergistic effect when used in combination with interferon-α. (E)-Hyzetimibe can be used for the study of HCV infection[1][2].

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