Mupirocin
CAS No. : 12650-69-0
(Synonyms: BRL-4910A; Pseudomonic acid)
| Size | Price | Stock |
|---|---|---|
| 5mg | $25 | In-stock |
| 10mg | $41 | In-stock |
| 25mg | $83 | In-stock |
| 50mg | $129 | In-stock |
| 100mg | $200 | In-stock |
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| Cat. No. : | HY-B0958 |
| M.Wt: | 500.62 |
| Formula: | C26H44O9 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis[1][2][3][4][5][6].
In Vitro:Mupirocin inhibits staphylococci and streptococci (except group D streptococci), with a MIC of ≤0.5 μg/mL[1].
Mupirocin (0.1-0.2 mM; 18 h) significantly increases wound closure and proliferation of human keratinocytes (HaCat) and enhances production of growth factors like HGF and PDGF-AA[4].
Mupirocin (≤125 μg/mL) reduces biofilm mass by greater than 90% in all S. aureus isolates[5].
In Vivo:Mupirocin (2%; topical application; twice daily; 3-6 days) reduces bacterial loads in murine superficial skin wounds infected with MRSA USA300[3].
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