OVA Peptide(257-264) (TFA)


CAS No. : 1262751-08-5

1262751-08-5
Price and Availability of CAS No. : 1262751-08-5
Size Price Stock
1mg $90 In-stock
5mg $170 In-stock
10mg $270 In-stock
25mg $460 In-stock
50mg $662 In-stock
100mg $945 In-stock
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Cat. No. : HY-P1489A
M.Wt: 1077.15
Formula: C47H75F3N10O15
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic)
Introduction of 1262751-08-5 :

OVA Peptide(257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. In Vitro:TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide(257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide(257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide(257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide(257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1].

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