Enarodustat (hydrochloride)
CAS No. : 1262131-60-1
(Synonyms: JTZ-951 (hydrochloride); SAL0951 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-109057A |
| M.Wt: | 376.79 |
| Formula: | C17H17ClN4O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
Enarodustat hydrochloride is a potent and orally active HIF/HIF Prolyl-Hydroxylase inhibitor, with an EC50 of 0.22 μM. Enarodustat hydrochloride has the potential for renal anemia treatment. IC50 & Target:pKi : 8.2 (5-HT2A receptor), 8.0 (D4 receptor), 6.7 (D2 receptor), 7.2 (α1 receptor), 6.9 (5-HT2C receptor), 5.7 (H1 receptor)[1] In Vitro: Enarodustat hydrochloride (JTZ-951) is a potent and orally active hypoxia-inducible factor prolyl hydroxylase inhibitor, with an EC50 of 0.22 μM. Enarodustat hydrochloride exhibits neither CYP (IC50 > 100 μM; CYP3A4/5, CYP2C9, CYP2D6, CYP1A2, CYP2A6, CYP2C19, CYP2C8, CYP2B6) nor hERG (IC50 > 100 μM) inhibition[1]. In Vivo: Enarodustat hydrochloride (1 and 3 mg/kg, p.o.) increases hemoglobin levels in a dose-dependent manner with daily oral dosing in rats[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Enarodustat (hydrochloride)
- Cat. No.:
- HY-109057A
- Quantity:
Your information is safe with us.