AM-0687


CAS No. : 1259522-94-5

1259522-94-5
Price and Availability of CAS No. : 1259522-94-5
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Cat. No. : HY-120471
M.Wt: 442.45
Formula: C23H19FN8O
Purity: >98 %
Solubility:
Introduction of 1259522-94-5 :

AM-0687 is a selective inhibitor for PI3Kδ with an IC50 of 2.9 nM. AM-0687 decreases the levels of IgG and IgM specific antibodies, inhibits the anti-IgM/CD40L-induced proliferation of human B cell (IC50=0.8 nM) and the phosphorylation of AKT (IC50=0.7 nM), and exhibits anti-inflammatory efficacy[1].

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