Sarpogrelate
CAS No. : 125926-17-2
(Synonyms: MCI-9042 (free acid))
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| Cat. No. : | HY-10563 |
| M.Wt: | 429.51 |
| Formula: | C24H31NO6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Sarpogrelate (MCI-9042) is a new, specific orally active 5-HT2 receptor antagonist, Sarpogrelate increases platelet aggregation and has hemostasis effect, and can be used for the research of Buerger’s disease[1].
In Vitro: Sarpogrelate (MCI-9042) induces a significant decrease in plasma serotonin (5-HT) concentration and after 2 weeks increases significantly the concentration of whole blood 5-HT[1].
Sarpogrelate increases significantly plasma tryptophan concentration after 2 and 4 weeks, and no changes in plasma 5-HIAA concentration[1].
Sarpogrelate also has a tendency to increase the concentration of whole blood tryptophan concentration, did not show significant changes in platelet aggregation induced by ADP and collagen[1].
Sarpogrelate increases significantly platelet aggregation induced by serotonin after 2 weeks[1].
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