TC-I 2014 (hydrochloride)


CAS No. : 1259026-14-6

1259026-14-6
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Cat. No. : HY-110199A
M.Wt: 503.87
Formula: C23H20ClF6N3O
Purity: >98 %
Solubility: 10 mM in H2O
Introduction of 1259026-14-6 :

TC-I 2014 hydrochloride is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 hydrochloride exhibits antiallodynic properties in pain models[1].

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