Venetoclax (Standard)
CAS No. : 1257044-40-8
(Synonyms: ABT-199 (Standard); GDC-0199 (Standard); RG7601 (Standard))
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| Cat. No. : | HY-15531R |
| M.Wt: | 868.44 |
| Formula: | C45H50ClN7O7S |
| Purity: | >98 % |
| Solubility: | DMSO : 77.5 mg/mL (89.24 mM; Need ultrasonic); Ethanol : < 1 mg/mL (insoluble) |
Venetoclax (Standard) is the analytical standard of Venetoclax. This product is intended for research and analytical applications. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy[1][2][3]. IC50 & Target:Ki: <0.01 nM (Bcl-2), 48 nM (Bcl-xl), 245 nM (Bcl-w), >444 nM (Mcl-1)[1]
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