Lavendustin C
CAS No. : 125697-93-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $48 | In-stock |
| 5mg | $111 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $444 | In-stock |
| 50mg | $800 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-W013857 |
| M.Wt: | 275.26 |
| Formula: | C14H13NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Lavendustin C is a potent Ca2+ calmodulin-dependent kinase II (CaMK II) inhibitor with an IC50 of 0.2 µM. Lavendustin C inhibits EGFR-associated tyrosine kinase (IC50=0.012 µM) and pp60c-src(+) kinase (IC50=0.5 µM) [1][2].
In Vitro: Lavendustin C (Compound 5) shows potent inhibitory activity, and it may be the core structure responsible for inhibition of tyrosine kinase[1].
Lavendustin C (10-150 µM) inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation[3].
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