Lavendustin B
CAS No. : 125697-91-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $166 | In-stock |
| 25mg | $360 | In-stock |
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| Cat. No. : | HY-108935 |
| M.Wt: | 365.38 |
| Formula: | C21H19NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Lavendustin B is an inhibitor of HIV-1 integrase interaction with LEDGF/p75 with an IC50 of 94.07 μM. Lavendustin B is an ATP-competitive GLUT1 inhibitor with a Ki of 15 µM. Lavendustin B is also a weak inhibitor of tyrosine kinases[1][2]. In Vitro: In HL-60 cells, Lavendustin B (0-1000 µM) inhibits the uptake of methylglucose, deoxyglucose, and dehydroascorbic acid in human erythrocytes in a dose-dependent manner, with 50% inhibition observed at approximately 10-30 µM. Moreover, increasing concentrations of Lavendustin B inhibited, in a dose-dependent manner, the binding of cytochalasin B to human erythrocyte membranes[1].
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