AI-10-49


CAS No. : 1256094-72-0

1256094-72-0
Price and Availability of CAS No. : 1256094-72-0
Size Price Stock
5mg $85 In-stock
10mg $128 In-stock
25mg $258 In-stock
50mg $388 In-stock
100mg $582 In-stock
200 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-16786
M.Wt: 660.52
Formula: C30H22F6N6O5
Purity: >98 %
Solubility: DMSO : ≥ 34 mg/mL
Introduction of 1256094-72-0 :

AI-10-49 is an inhibitor of leukemic oncoprotein CBFβ-SMHHC. AI-10-49 inhibits the binding of CBFβ-SMMHCto the RUNX1 Runt domain with IC50 value of 0.26 μM. AI-10-49 can be used for the research of leukemia[1]. In Vitro:AI-10-49 inhibits the binding of CBFβ-SMMHCto theRUNX1 Runt domain with IC50 value of 0.26 μM[1].
AI-10-49 (1 μM; 3, 6, 12 hours) has selectivity for inhibiting CBFβ-SMMHC binding to RUNX1[1]. In Vivo:AI-10-49 (200 mg/kg; per day) delays leukemia progression in mice[1].

Your information is safe with us.