Saclofen (Standard)


CAS No. : 125464-42-8

125464-42-8
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Cat. No. : HY-100813R
M.Wt: 249.72
Formula: C9H12ClNO3S
Purity: >98 %
Solubility:
Introduction of 125464-42-8 :

Saclofen (Standard) is the analytical standard of Saclofen. This product is intended for research and analytical applications. Saclofen is an orally active and a competitive GABAB receptor antagonist with an IC50 of 7.8 μM, but has weak antagonism against GABAB1b and GABAB2 heterodimeric recombinant receptors. Saclofen inhibits the binding of Baclofen (HY-B007) to rat cerebellar membranes and blocks Baclofen-induced circadian phase shifts, and exhibits anti-inflammatory and analgesic effects in rats[1][2][3][4][5].

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