Icosabutate (Standard)
CAS No. : 1253909-57-7
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| Cat. No. : | HY-121212R |
| M.Wt: | 374.56 |
| Formula: | C24H38O3 |
| Purity: | >98 % |
| Solubility: |
Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis[1][2][3][4]. IC50 & Target:IC50: non-HDL-C[2]
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