Vinorelbine (ditartrate)
CAS No. : 125317-39-7
(Synonyms: KW-2307; Nor-5'-anhydrovinblastine ditartrate)
| Size | Price | Stock |
|---|---|---|
| 5mg | $40 | In-stock |
| 10mg | $65 | In-stock |
| 25mg | $136 | In-stock |
| 50mg | $238 | In-stock |
| 100mg | $409 | In-stock |
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| Cat. No. : | HY-12053A |
| M.Wt: | 1079.11 |
| Formula: | C53H66N4O20 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : 175 mg/mL (ultrasonic) |
Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM. In Vitro:Vinorelbine (0.5-5 nM) ditartrate inhibits cell proliferation by 50% (IC50) at concentrations of 1.25 nM. At a concentration of 8 nM, no cells are in anaphase[1]. Vinorelbine ditartrate time-dependently induces the p53 and p21WAFI/CIP1 expression in androgen-dependent (AD) and- independent (AI) prostate cancer cell lines. Vinorelbine ditartrate stimulates reporter genes in a concentration-dependent manner[2].
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