GB83
CAS No. : 1252806-86-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $95 | In-stock |
| 5mg | $240 | In-stock |
| 10mg | $395 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-124061 |
| M.Wt: | 548.72 |
| Formula: | C32H44N4O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 40 mg/mL (ultrasonic;warming) |
GB83 is a potent PAR2 antagonist. GB83 reverses neutrophil elastase‐induced synovitis and pain. GB83 blocks the effect of MET-1 supernatant on NG neurons[1]. In Vitro: GB83 (10 µM) blocks the effect of MET-1 (microbial ecosystem therapeutic-1) supernatant on nodose ganglion (NG) neurons[2]. In Vivo: GB83 (5 µg; i.p.) reverses neutrophil elastase‐induced synovitis and pain in PAR2 KO mice[1].
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