Vomicine


CAS No. : 125-15-5

125-15-5
Price and Availability of CAS No. : 125-15-5
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5mg $160 In-stock
10mg $240 In-stock
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Cat. No. : HY-N2616
M.Wt: 380.44
Formula: C22H24N2O4
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 125-15-5 :

Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds[1][2]. In Vitro:Vomicine (0-100 μM, 72 h) inhibits the mRNA and proteins expressions of cGAS, STING, IRF3, IL-6 and IFN-β in mutated SOD expressiong neuronal cell hSOD1G93A NSC-34, improves the morphology of hSOD1G93A NSC-34[2].

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