Prednisone acetate
CAS No. : 125-10-0
(Synonyms: Prednisone 21-acetate)
| Size | Price | Stock |
|---|---|---|
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| 1g | $60 | In-stock |
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| Cat. No. : | HY-B1832 |
| M.Wt: | 400.46 |
| Formula: | C23H28O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].
In Vivo:Prednisone acetate (5 mg/kg, Intragastric gavage, once a day for 4 weeks) induces hippocampal LTP impairment by causing neuronal lesions in the dentate gyrus, which reduced glutamic acid (Glu) and NMDAR2A, and impaired spatial memory in Hippocampal LTP impairment model mice[1].
Prednisone acetate (6 mg/kg, gavage, once a day for 15 days) reduces ocular and peripheral inflammatory responses and restores Th1/Th2 and Th17/Treg immune homeostasis through orchestrating the Notch signaling pathway in Experimental autoimmune uveitis (EAU) rats[2].
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