USP7/USP47 inhibitor


CAS No. : 1247825-37-1

1247825-37-1
Price and Availability of CAS No. : 1247825-37-1
Size Price Stock
5mg $115 In-stock
10mg $200 In-stock
25mg $360 In-stock
50mg $576 In-stock
100mg $945 In-stock
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Cat. No. : HY-13487
M.Wt: 484.40
Formula: C18H11Cl2N3O3S3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1247825-37-1 :

USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively. IC50 & Target: EC50: 0.42 μM (USP7), 1.0 μM (USP47)[1] In Vitro: USP7/USP47 inhibitor (compound 14) is a selective inhibitor of USP7/USP47 with EC50s of 0.42 μM and 1 μM, respectively. USP7/USP47 inhibitor does not inhibit caspase 3, calpain 1, 20S proteasome, and a panel of representative USPs (USP2, USP5, USP8, USP21, and USP28; EC50 > 31.6 μM). USP7/USP47 inhibitor inhibits the growth of HCT-116 cells with an EC50 of 7.6 μM[1].

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