Propargyl-PEG5-acid


CAS No. : 1245823-51-1

1245823-51-1
Price and Availability of CAS No. : 1245823-51-1
Size Price Stock
250mg $33 In-stock
1g $55 In-stock
5g $275 In-stock
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Cat. No. : HY-101157
M.Wt: 304.34
Formula: C14H24O7
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1245823-51-1 :

Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-acid is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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