TK05


CAS No. : 1245734-61-5

1245734-61-5
Price and Availability of CAS No. : 1245734-61-5
Size Price Stock
5mg $540 In-stock
10mg $880 In-stock
25mg $1750 In-stock
50mg $2800 In-stock
100mg $4500 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-117143
M.Wt: 540.99
Formula: C31H25ClN2O5
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 1245734-61-5 :

TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM[1]. IC50 & Target: IC50: 95 nM (Leukotriene C4 synthase)[1] In Vitro: TK05 reduces LTC4 production in a dose-dependent manner with an IC50 value of 318 ± 60 nM in MM6 Cells[1]. In Vivo: TK05 (0.12-6 mg/kg; given i.p.; only once) significantly reduces LTE4 levels[1].

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