Omaciclovir


CAS No. : 124265-89-0

(Synonyms: H2G)

124265-89-0
Price and Availability of CAS No. : 124265-89-0
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1mg $150 In-stock
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Cat. No. : HY-116174
M.Wt: 253.26
Formula: C10H15N5O3
Purity: >98 %
Solubility: DMSO : 230 mg/mL (ultrasonic)
Introduction of 124265-89-0 :

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity[1]. In Vitro: Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys[1].
Omaciclovir shows antiviral activities against different human herpesviruses with EC50s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively[1].

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