FN-439
CAS No. : 124168-73-6
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| Cat. No. : | HY-100210 |
| M.Wt: | 490.55 |
| Formula: | C23H34N6O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2].
In Vitro: FN-439 inhibits collagenase-1 with an IC50 value of
1 μM[1].
FN-439 (1 μM) reduces the invasive potential of MDA-MB-231 breast cancer cells[1].
In Vivo: FN-439 significantly decreases neutrophils and macrophages, shows extensive bone formation and active cementogenesis in the periapical region when has a combination with ofloxaci[2].
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