(R)-DRF053 (dihydrochloride)


CAS No. : 1241675-76-2

1241675-76-2
Price and Availability of CAS No. : 1241675-76-2
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1mg $175 In-stock
5mg $435 In-stock
10mg $740 In-stock
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Cat. No. : HY-103383
M.Wt: 490.43
Formula: C23H29Cl2N7O
Purity: >98 %
Solubility: DMSO : 49.04 mg/mL (ultrasonic;warming)
Introduction of 1241675-76-2 :

(R)-DRF053 dihydrochloride is a potent casein kinases 1 (CK1), CDK1/cyclin B and CDK5/p25 inhibitor with IC50s of 14 nM, 220 nM and 80 nM, respectively. (R)-DRF053 dihydrochloride prevents the CK1-dependent production of amyloid-beta in a cell model[1].

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