EXEL-0346
CAS No. : 1239893-96-9
Price and Availability of
CAS No. : 1239893-96-9
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|---|---|---|
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| Cat. No. : | HY-112488 |
| M.Wt: | 580.44 |
| Formula: | C27H29BrF3N3O3 |
| Purity: | >98 % |
| Solubility: |
Introduction of
1239893-96-9
:
EXEL-0346 is an orally active glucosylceramide synthase (GCS) inhibitor, with an IC50 of 2 nM. EXEL-0346 combined with insulin increases pAkt. EXEL-0346 effectively reduces the levels of Glucosylceramide, Lactosylceramide and GM3. EXEL-0346 improves obesity and diabetes[1]. IC50 & Target:IC50: 2 nM (GCS)[1]
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- Cat. No.:
- HY-112488
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