Almokalant
CAS No. : 123955-10-2
(Synonyms: H 234/09)
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| Cat. No. : | HY-106855 |
| M.Wt: | 352.49 |
| Formula: | C18H28N2O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. IC50 & Target: Potassium channel[1] In Vitro: Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current[1]. In Vivo: Almokalant (125 μmol/kg, p.o.) induces cardiovascular defects, orofacial clefts, and tail defects in pregnant rats, after administration on Day 11. Almokalant also causes in pregnant rats[1].
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