Hypocrellin B
CAS No. : 123940-54-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $480 | In-stock |
| 50mg | $720 | In-stock |
| 100mg | $1080 | In-stock |
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| Cat. No. : | HY-N1453 |
| M.Wt: | 528.51 |
| Formula: | C30H24O9 |
| Purity: | >98 % |
| Solubility: | DMSO : 2 mg/mL (ultrasonic) |
Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities[1][2][3].
In Vitro:Hypocrellin B (2.5 μM, 4 h) induces cell cytotoxicity 24 h after sonodynamic therapy (SDT) in HepG2 cells, and induces induce the early apoptosis[2].
Hypocrellin B shows antifungal and anti-parasite activity against C. albicans and Leishmania donovani respectively (IC50: 5 and 12.7 μg/mL)[3].
In Vivo:Hypocrellin B (2 mg/kg, i.v.) inhibits tumor growth in A549 tumor bearing mice, but the anticancer efficacy is less than hypocrellin B loaded nanoparticles[4].
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