Henatinib (maleate)
CAS No. : 1239269-52-3
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| Cat. No. : | HY-13645A |
| M.Wt: | 584.59 |
| Formula: | C29H33FN4O8 |
| Purity: | >98 % |
| Solubility: |
Henatinib maleate is an orally active small-molecule multikinase inhibitor that has demonstrated broad and potent antitumor activities. Henatinib maleate inhibits the activity of VEGFR-2, c-kit, PDGFR with IC50 values of 0.6 nM, 3.3 nM and 41.5 nM, respectively. Henatinib maleate significantly inhibits VEGFR-2 phosphorylation and its downstream signal pathway[1][2].
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