Moracin O
CAS No. : 123702-97-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $196 | In-stock |
| 5mg | $490 | In-stock |
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| Cat. No. : | HY-N3244 |
| M.Wt: | 326.34 |
| Formula: | C19H18O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects[1][2][3]. In Vitro: Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC50 value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD[1].
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