CGP36216
CAS No. : 123691-29-2
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| Cat. No. : | HY-103518 |
| M.Wt: | 151.14 |
| Formula: | C5H14NO2P |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CGP36216 is a selective antagonist at GABA presynaptic receptor. CGP36216 binds to GABAB receptor with a Ki value of 0.3 μM. CGP36216 hydrochloride can be used for research of anxiety and trauma-related disorders[1][2].
IC50 & Target:GABAB receptor[1]
In Vitro:CGP36216 is ineffective at GABA postsynaptic receptors, it is appreciably more active at presynaptic receptors[2].
CGP36216 (100 µM) could increase the frequency of spontaneous firing in VTA-DA neurons[3].
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