BMS-520
CAS No. : 1236188-38-7
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| Cat. No. : | HY-120615 |
| M.Wt: | 470.40 |
| Formula: | C23H17F3N4O4 |
| Purity: | >98 % |
| Solubility: |
BMS-520 is a potent, orally active and selective sphingosine-1-phosphate 1 (S1P1) agonist with an EC50 of 0.47nM. BMS-520 shows ~3400-fold selectivity over S1P3. BMS-520 demonstrates impressive efficacy in a rat model of arthritis and in a mouse experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis. BMS-520 can be used for arthritis and EAE research[1].
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