PF-04856264
CAS No. : 1235397-05-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $460 | In-stock |
| 50mg | $730 | In-stock |
| 100mg | $1200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12811 |
| M.Wt: | 437.49 |
| Formula: | C20H15N5O3S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C) |
PF-04856264 is a potent and selective Nav1.7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1.7, respectively. PF-04856264 has low potency against the rat Nav1.7 channel. PF-04856264 shows analgesic effect[1][2]. IC50 & Target: IC50: 28 (human Nav1.7), 131 nM (mouse Nav1.7), 19 nM (cynomolgus monkey Nav1.7), 42 nM (dog Nav1.7)[1] In Vivo: PF-04856264 (3-30 mg/kg; i.p.) reverses OD1-induced pain behaviors[2].
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- HY-12811
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