Globalagliatin


CAS No. : 1234703-40-2

(Synonyms: LY2608204; SY-004)

1234703-40-2
Price and Availability of CAS No. : 1234703-40-2
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Cat. No. : HY-13529
M.Wt: 559.81
Formula: C28H37N3O3S3
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 1234703-40-2 :

Globalagliatin (LY2608204) is an orally active glucokinase (GK) activator with an EC50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with an EC50 of 579 nM. Globalagliatin targets both pancreatic β-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes[1][2][3]. In Vitro:Globalagliatin (LY2608204) displays no selective inhibitory effect under 5 µM in DNMT3A R882H cells[4].

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