Epetraborole (hydrochloride)
CAS No. : 1234563-16-6
(Synonyms: GSK2251052 hydrochloride)
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $140 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $510 | In-stock |
| 50mg | $690 | In-stock |
| 100mg | $950 | In-stock |
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| Cat. No. : | HY-12479A |
| M.Wt: | 273.52 |
| Formula: | C11H17BClNO4 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 28 mg/mL;DMSO : 200 mg/mL (ultrasonic) |
Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor (IC50=0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research[1][2][3]. IC50 & Target:IC50: 0.31 μM (LeuRS)[3] In Vitro:Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes[1].
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