CAS No. : 123408-98-0
(Synonyms: Inositol hexaphosphate (dodecasodium hydrate); SNF472 (dodecasodium hydrate))
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| Cat. No. : | HY-N0814A |
| M.Wt: | 1000.00 |
| Formula: | C6H6O24P6.xH2O.12Na |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 250 mg/mL;10 mM in DMSO |
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4]. IC50 & Target:Xanthine oxidase[3] In Vitro: Phytic acid dodecasodium hydrate (myo-Inositol) inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by Phytic acid dodecasodium salt hydrate; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[3].
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