CAY10650
CAS No. : 1233706-88-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $225 | In-stock |
| 25mg | $450 | In-stock |
| 50mg | $630 | In-stock |
| 100mg | $850 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-10801 |
| M.Wt: | 471.50 |
| Formula: | C28H25NO6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion[1][2].
In Vitro:CAY10650 (12 nM; 30 min; neutrophils) inhibits the expression of the phosphorylated cPLA2-α (p-cPLA2-α) in cells[1].
CAY10650 (12 nM; 2 h; neutrophils) inhibits PGE2 release in neutrophils[1].
In Vivo:CAY10650 (50 μg/5 μL; Inject with topical eye-drop; Chinese hamsters) relieves acanthamoeba keratitis in vivo.[1].
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