Surotomycin


CAS No. : 1233389-51-9

(Synonyms: CB-183,315)

1233389-51-9
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Cat. No. : HY-107119
M.Wt: 1680.72
Formula: C77H101N17O26
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1233389-51-9 :

Surotomycin (CB-183, 315) is an orally active cyclic lipopeptide. Surotomycin has antibacterial activity against C. difficile with a MIC90 value of 0.5 μg/mL. Surotomycin can be used for the research of clostridium difficile-associated diarrhea (CDAD)[1]. IC50 & Target:MIC90: 0.5 μg/mL(C. difficile)[1] In Vitro: Surotomycin exhibits significantly improved in vitro antibacterial activity against C. difficile with a MIC90 value of 0.5 μg/mL[1].
Surotomycin shows improvement in activity against 28 DAP nonsusceptible S. aureus strains[1]. In Vivo: Surotomycin (P.O.; 0.5 mg/kg; once daily for 5 consecutive days) protects animals in hamster efficacy studies[1].

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