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| Cat. No. : | HY-107119 |
| M.Wt: | 1680.72 |
| Formula: | C77H101N17O26 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Surotomycin (CB-183, 315) is an orally active cyclic lipopeptide. Surotomycin has antibacterial activity against C. difficile with a MIC90 value of 0.5 μg/mL. Surotomycin can be used for the research of clostridium difficile-associated diarrhea (CDAD)[1].
IC50 & Target:MIC90: 0.5 μg/mL(C. difficile)[1]
In Vitro: Surotomycin exhibits significantly improved in vitro antibacterial activity against C. difficile with a MIC90 value of 0.5 μg/mL[1].
Surotomycin shows improvement in activity against 28 DAP nonsusceptible S. aureus strains[1].
In Vivo: Surotomycin (P.O.; 0.5 mg/kg; once daily for 5 consecutive days) protects animals in hamster efficacy studies[1].
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