Phyltetralin
CAS No. : 123048-17-9
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| Cat. No. : | HY-121397 |
| M.Wt: | 416.51 |
| Formula: | C24H32O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system[1][2].
In Vitro: Phyltetralin shows inhibition on Polymorphonuclear neutrophil (PMN) chemotaxis with an IC50 of 4.01 µM[2].
Phyltetralin shows strong inhibition against reactive oxygen species (ROS) production from PMA-stimulated neutrophil with an IC50 of 0.73 µM[2].
Phyltetralin shows weak inhibition on CD18 expression and moderate inhibition on engulfment activity[2].
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