Azelaic acid
CAS No. : 123-99-9
(Synonyms: Nonanedioic acid)
| Size | Price | Stock |
|---|---|---|
| 500g | $32 | In-stock |
| 1000g | $55 | In-stock |
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| Cat. No. : | HY-B0704 |
| M.Wt: | 188.22 |
| Formula: | C9H16O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals[1][2].
In Vitro:Azelaic acid (0.5 M; 48 h-7 D) has antimicrobial effect[3].
Azelaic acid (5 M; 24 h) decreases intracellular Reactive Oxygen Species (ROS) levels and increases antioxidant capacity[5].
Azelaic acid (1-100 mM, 24 h) suppresses B16, HMB2, and SK23 cell survival ability in a dose-dependent manner[6].
In Vivo:Azelaic acid (15% gel; Smear; twice daily) in 15% gel is efficacious in people with moderate papulo-pustular[4].
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