Secukinumab
CAS No. : 1229022-83-6
(Synonyms: AIN457)
| Size | Price | Stock |
|---|---|---|
| 1mg | $180 | In-stock |
| 5mg | $620 | In-stock |
| 10mg | $990 | In-stock |
| 25mg | $1850 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-P9927 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O |
Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis[1][2].
In Vitro: Secukinumab is a fully human monoclonal antibody that selectively binds to and neutralizes interleukin-17A[2].
Secukinumab (1 nM, 10 nM, and 100 nM) inhibits IL17A and IL17A/TNF a-induced increase in protein levels of IL6 in human astrocytes[3].
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