Methdilazine (hydrochloride)


CAS No. : 1229-35-2

1229-35-2
Price and Availability of CAS No. : 1229-35-2
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1mg $150 In-stock
5mg $340 In-stock
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Cat. No. : HY-B1690A
M.Wt: 332.89
Formula: C18H21ClN2S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1229-35-2 :

Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2]. In Vitro: Methdilazine hydrochloride (0-20 μg/mL approximately, 18 h) inhibits kinds of mycobacterium with MIC values ranging from 5 μg/mL to 15 μg/mL[1].
In Vivo: Methdilazine hydrochloride (Intraperitoneal injection, 10 μg/gm body wt/day, 6 weeks) is antagonistic to mycobacteria in H37Rv infected mice[1].
Methdilazine hydrochloride (Oral administration, 10 mg/kg per day, 28 days) improves survival of Mycobacterium Tuberculosis (Mtb) H37Rv infected mice[2].

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