Mps1-IN-2
CAS No. : 1228817-38-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $85 | In-stock |
| 10mg | $130 | In-stock |
| 25mg | $245 | In-stock |
| 50mg | $390 | In-stock |
| 100mg | $600 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-13994 |
| M.Wt: | 480.60 |
| Formula: | C26H36N6O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 13.33 mg/mL (ultrasonic) |
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor, with an IC50 and a Kd of 145 nM and 12 nM for Mps1 and a Kd of 61 nM for Plk1.
IC50 & Target: IC50: 145 nM (Mps1)[1]
Kd: 12 nM (Mps1)[1]
In Vitro: Mps1-IN-2 is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 145 nM and 12 nM. Mps1-IN-2 also shows high affinity for PLK1 and GAK with Kds of 61 and 140 nM, respectively, but shows little or no inhibition on other 352 member kinases. Mps1-IN-2 can induces bypass of a checkpoint-mediated mitotic arrest in U2OS cells[1].
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- Mps1-IN-2
- Cat. No.:
- HY-13994
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