CDE-096
CAS No. : 1228357-04-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $162 | In-stock |
| 10mg | $270 | In-stock |
| 25mg | $567 | In-stock |
| 50mg | $908 | In-stock |
| 100mg | $1454 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-120516 |
| M.Wt: | 583.42 |
| Formula: | C25H20F3NO12 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
CDE-096 is a potent inhibitor of PAI-1. CDE-096 prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively) and is active against glycosylated PAI-1, as well as PAI-1 derived from several species (IC50=19, 22 and 18 nM for murine, rat, and Porcine PAI-1, respectively)[1]. In Vitro: CDE-096 is active against both free PAI-1 and vitronectin-bound PAI-1. CDE-096 binds to PAI-1 with nanomolar affinity and induces conformational changes that prevent binding to both proteases and vitronectin[1].
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