SMCC-DM1


CAS No. : 1228105-51-8

(Synonyms: DM1-SMCC)

1228105-51-8
Price and Availability of CAS No. : 1228105-51-8
Size Price Stock
1mg $120 In-stock
5mg $180 In-stock
10mg $330 In-stock
25mg $750 In-stock
50mg $1200 In-stock
100mg $1680 In-stock
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Cat. No. : HY-101070
M.Wt: 1072.61
Formula: C51H66ClN5O16S
Purity: >98 %
Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 1228105-51-8 :

SMCC-DM1 (DM1-SMCC) is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody drug conjugate (ADC)[1]. In Vitro: SMCC-DM1 inhibits HCC1954 and MDA-MB-468 cells proliferation with IC50s of 17.2 and 49.9 nM, respectively[1].

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