LCB 03-0110
CAS No. : 1228102-01-9
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|---|---|---|
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| Cat. No. : | HY-110367A |
| M.Wt: | 417.52 |
| Formula: | C24H23N3O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
LCB 03-0110, a thienopyridine derivative, is a potent pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor. LCB 03-0110 suppresses scar formation by inhibiting fibroblast and macrophage activation[1]. In Vitro:LCB 03-0110 suppresses the proliferation and migration of primary dermal fibroblasts induced by transforming growth factor β1 and type I collagen[1]. In Vivo:LCB 03-0110 suppresses the accumulation of myofibroblast and macrophage cells in the healing wound and reduced hypertrophic scar formation after wound closing on rabbit ears[1].
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