GNF351
CAS No. : 1227634-69-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $107 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $360 | In-stock |
| 50mg | $660 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-102023 |
| M.Wt: | 411.50 |
| Formula: | C24H25N7 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes[1]. IC50 & Target: IC50: 62 nM (aryl hydrocarbon receptor)[1] In Vitro: GNF351 (500 nM, 48 hours) significantly reduces the percentage of Ki67-positive cells and cell number after treating proliferating monolayer cultures of human keratinocytes[1].
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