GN25
CAS No. : 1227401-27-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $46 | In-stock |
| 10mg | $75 | In-stock |
| 25mg | $155 | In-stock |
| 50mg | $250 | In-stock |
| 100mg | $420 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-117280 |
| M.Wt: | 322.33 |
| Formula: | C15H14O6S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C) |
GN25 is a specific p53-Snail binding inhibitor with antitumor effects[1].
In Vitro: GN25 (10 and 20 μM; 24 h) inhibits cell viability of K-Ras-mutated MEF cells[1].
GN25 (5 μM; 4 h) activates p53 in a K-Ras-dependent manner[1].
GN25 (1-10 μM; 1-6 h) induces p53 and p21 in a dose- and time- dependent manner in K-Ras-mutated A549 and HCT116 cell lines[1].
GN25 activates wild-type p53 in p53WT/MT cells[1].
GN25 (0.25 μM) recovers the masking effect of p53 on CK1/GSK3b-mediated Snail phosphorylation[1].
In Vivo: GN25 (10 and 20 mg/kg; i.p. once a week for 10 weeks) blocks the tumor progression and induces tumor regression in mice[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- GN25
- Cat. No.:
- HY-117280
- Quantity:
Your information is safe with us.