AMG 579
CAS No. : 1227067-61-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $220 | In-stock |
| 25mg | $380 | In-stock |
| 50mg | $530 | In-stock |
| 100mg | $750 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-12913 |
| M.Wt: | 441.48 |
| Formula: | C25H23N5O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 41.67 mg/mL (ultrasonic) |
AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. IC50 & Target: IC50: 0.1 nM (Phosphodiesterase 10A)[1] In Vivo: AMG 579 shows statistically significant reduction of PCP induced behavior in rats over the 2 h period. Minimum effective doses for efficacy in PCP-LMA model is determined to be 0.3 mg/kg for AMG 579. In dog, 5 exhibits superior oral bioavailability of 72%[1].
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